The synapse: center stage for many brain diseases

Epigenetics in Brain Tumors: HDACs Take Center Stage

Primary tumors of the brain account for 2 % of all cancers with malignant gliomas taking the lion's share with 70 %. Malignant gliomas (high grade gliomas WHO° III and °IV) belong to one of the most threatening tumor entities known with their disappointingly short median survival time of just 14 months despite maximum therapy according to current gold standards. Malignant gliomas secrete variou...

Moving the Case for Equity Center Stage

Marilyn A. DeLuca, PhD, RN, is a leader in global health, systems, and workforce. Founder of the consultancy Global Health-Health Systems-Philanthropy, she is lead co-editor of the recent book, Transforming the Global Health Workforce (DeLuca and Soucat, 2013). A registered professional nurse, she is a research assistant professor in the School of Medicine and adjunct associate professor in the...

A Link between Cholesterol, Cns, Synapse and Brain Diseases: Is There a Need for a Reinvention?

E-containing lipoproteins may function to redistribute lipid and regulate cholesterol homeostasis within the brain". In 1993 we learned about the importance of "cholesterol synthesis and lipoprotein reuptake during synaptic remodeling". Over the past decade this knowledge was amassed (thanks to the pivotal contribution by many scientists) and elucidated the role for the failure of cholesterol h...

MULTIPLIER ANALYSIS IN THE FRAMEWORK OF MANY PRODUCERS AND MANY CONSUMERS OF THE SAM FOR THE IRANIAN ECONOMY

Innovation center stage.

One lesser known element of the Patient Protection and Affordable Care Act was the establishment in 2011 of the Center for Medicare and Medicaid Innovation (CMMI), a federal program administered by the US Department of Health and Human Services. With a $10 billion funding commitment over its first decade of operation, the goal of CMMI is to test innovative payment and service delivery models to...